Platelet donor database

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Single donor platelet transfusion.

Cytopheresis equipment from a number of manufacturers now permits the rapid, safe, and efficient procurement of functionally normal platelets from single donors. There has been an extensive proliferation of these blood cell separators and virtually all large blood collection centers and most large hospitals have at least one blood cell separator in operation. Transfusions from single donors sel...

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Refractoriness to platelet transfusion after single-donor consecutive platelet transfusions and its relationship to platelet antibodies.

In thirty patients with acute leukemia and severe aplastic anemia receiving random single donor platelet transfusions, the development of refractoriness by consecutive platelet transfusions with cytapheresis and its relationship to the appearance of anti-platelet antibodies were investigated. The median number of platelet transfusions inducing refractoriness was 13 times, and 20% of the patient...

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Selection of histocompatible apheresis platelet donors by cross-matching random donor platelet concentrates.

It can be impossible to identify compatible platelet donors for alloimmunized patients whose HLA type cannot be determined or who have uncommon HLA types. We have previously shown that histocompatible donors can be rapidly identified by "mass screening" of platelet concentrates (PC), which are readily available in all blood banks, using a solid-phase adherence platelet cross-matching technique....

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Platelet transfusion therapy. Optimal donor selection with a combination of lymphocytotoxicity and platelet fluorescence tests.

Although the value of HLA matching for the selection of platelet donors for patients refractory to random platelets is beyond doubt, even perfectly matched combinations sometimes fail to give a satisfactory transfusion response. With HLA typing and negative lymphocytotoxicity crossmatches, 35% of the platelet transfusions administered to 15 patients gave disappointing results (29 of 82). Additi...

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Correlation of platelet concentration in platelet-rich plasma to the extraction method, age, sex, and platelet count of the donor.

An important reason to improve methods of isolating platelet-rich plasma (PRP) is the potential use of autologous platelet growth factors. In addition to discontinuous plasma separation, a second method for extraction of PRP has now become available, which can be performed directly by the surgeon. In this study, the suitability of the 2 methods of producing PRP was compared. Whole blood was dra...

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ژورنال

عنوان ژورنال: Chinese Medical Journal

سال: 2021

ISSN: 2542-5641

DOI: 10.1097/cm9.0000000000001561